Round 4: Tossup 15

The Fahrni group pioneered cellular detection of this element using tetrathiazacrown (“tetra-THY-uh-za-crown”) ether probes. This metal is needed for beta-monooxygenases to convert dopamine into norepinephrine. This metal can be delivered to its ATP7A transporter while bound to ceruloplasmin. This metal’s iodide is notably not required when using cyclooctynes (“cyclo-OCK-tynes”) developed by the Bertozzi group in a variant (10[1])of click chemistry “free” of it. Zinc and this metal are coordinated in the most common family of eukaryotic superoxide dismutases. (-5[1])ParaGard is among a class of IUDs coated in this metal. Epoxide ring openings in alkaloid syntheses often use lithium and this metal in the form of Gilman reagents. Oxygen is bound to this metal in hemocyanin giving spider blood a blue hue. For 10 points, name this element whose symbol is Cu. ■END■ (10[2])

Back to tossups

Buzzes

Summary