Round 8: Tossup 7

Gomori-positive subsets of these non-muscle cells are rich in degenerated mitochondria. Corkscrew-shaped aggregates called Rosenthal fibers are mostly composed of these cells’ namesake fibrillary (10[1])acidic protein. EAAT1/2 (“E-A-A-T-one-two”) facilitates the reuptake of glutamate into these cells. In response to injury, chondroitin sulfate proteoglycans produced by these cells accumulate in their namesake scars. The alkylating agent temozolomide (-5[1])is used to treat WHO Grade III and IV blastomas of these cells. The Bergmann type of these cells is abundant in the Purkinje layer. Synaptic pruning is mediated (-5[1])by phagocytic “micro” forms of these cells. (-5[1])Star-shaped types of these cells (10[1])have foot processes that form the blood-brain barrier. (10[1])For 10 points, name these supportive non-neuronal cells (-5[2])of the CNS. ■END■ (10[3]0[2])

ANSWER: glial cells [accept neuroglial cells or neuroglia; accept macroglia or microglia; accept astroglia or astrocytes; accept radial glial cells or RGCs or radial glial progenitor cells or RGPs; accept Muller glia; accept Bergmann glia; accept glial fibrillary acidic protein or GFAP; accept glial scars or gliosis; accept glioblastomas or astrocytomas; prompt on brain cells; prompt on macrophages or leukocytes or phagocytes until read by asking “what non-immune function do they also serve?”; reject “neurons” or “nerve cells”]
<Southampton A, Biology> | Packet J - Southampton A, Indiana A, Illinois B, Edinburgh A
= Average correct buzzpoint

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