amino acids - 2026 ACF Regionals

Packet G: Tossup 6

TOAC (“T-O-A-C”) is a cyclic, radical one of these compounds used as a spin label in EPR spectroscopy. Isotope-labeled versions of these compounds are used in SILAC (“SYE-lack”) experiments. (10[3])Derivatives (-5[1])of one of these compounds react with boroxines (“bor-OCK-seens”) to form asymmetric Corey–Bakshi–Shibata catalysts. These compounds are conjugated (10[2])onto Wang (10[1])resins using coupling agents (10[1])like (10[1])benzotriazoles (10[1])or (10[1])carbodiimides (10[1])(“carbo-die-IM-mydes”) in Merrifield solid-phase (10[1])synthesis. (10[1]-5[1])In that method, (10[1])these compounds (10[1])must be protected by (10[1])groups (10[1])like Boc (10[2])(“bock”) and Fmoc (10[7])(“F-mock”). These (10[1])compounds are formed (-5[1])by treating (-5[1])an aldehyde with hydrogen cyanide (-5[1])then hydrolysis during the Strecker (10[1])synthesis. (10[9]-5[4])Simple (10[2])examples (10[1])of these (-5[1])compounds can be (10[1])formed by (10[1])electrical discharges, (10[2])as demonstrated by Miller and Urey. (10[2]-5[1])For (10[1]-5[1])10 points, (10[4])name these (10[1])building blocks (10[3])for polypeptides. (10[4])■END■ (10[18]0[2])

ANSWER: amino acids [or AAs; accept alpha- or beta- amino acids; accept L- or D- amino acids; accept prolines; accept peptides or dipeptides or polypeptides or solid-phase peptide synthesis until read; accept SPPS; accept proteins; prompt on amines; prompt on carboxylic acids] (TOAC is 2,2,6,6-tetramethylpiperidine-N-oxyl-4- amino-4-carboxylic acid.)

<Rutgers A/NYU A/McMaster A, Chemistry> | Packet G - McMaster A, Notre Dame C, Rutgers A, NYU A

= Average correct buzzpoint

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Buzzes

Player	Team	Opponent	Buzzpoint	Value
Samarth Ram	Chicago B	Illinois C	26	10
Oscar Despard	Cambridge A	Oxford A	26	10
Roselyn Daffin	Southampton B	City St. George's	26	10
Krishna Girish	Montpellier	LSE	27	-5
Russell Nip	UBC A	Western C	44	10
Mason Yu	Brown	Brandeis A	44	10
Rohan Ganeshan	Harvard A	Harvard B	46	10
Tianyu Xu	Georgia Tech B	Louisville B	50	10
Andrew Wang	Illinois A	Purdue A	51	10
Shiva Tegulla	Central Florida A	Central Florida C	52	10
Eugenia Tong	Imperial A	Manchester	53	10
Zach Tseng	Georgia Tech C	Alabama A	54	10
Jack Lewis	Bruin	Tennessee A	57	10
Ezra Santos	Chicago A	Indiana A	58	-5
Matthew He	Texas A	Texas A&M A	58	10
Karthik Jayaram	UCLA A	UC Santa Barbara	61	10
Braden Booth	Missouri A	Missouri B	63	10
Pace Klein	CWRU A	Ohio State C	67	10
Ilyas Choukri	Virginia Tech A	Duke	68	10
Yusuf Baig	McMaster B	Toronto D	70	10
Yoyo Liu	UBC B	Waterloo A	70	10
Alden Thompson	Carleton University	Simon Fraser	72	10
Jason Zhang	Toronto B	Toronto Metropolitan	72	10
Liam Rojas	Virginia	Liberty A	72	10
Andres Cordoba	Yale	Southern Connecticut State	72	10
Rohan Dalal	Georgia Tech A	Iowa State	72	10
Ted Harrison	Edinburgh B	Birmingham	72	10
Ali Hamzeh	Edinburgh A	Cambridge B	72	10
Yashwanth Bajji	Michigan A	Michigan C	73	10
Oliver West	Cambridge C	Warwick B	76	-5
Tiffany Zhou	Ohio State A	Pittsburgh	78	-5
James O'Reilly	Arizona State	UC Irvine	83	-5
Jason Thieu	Michigan State	Ohio State B	88	10
Vinu Harihar	Berkeley B	Stanford A	89	-5
Fish Tsai	UCSD A	UCSD C	89	-5
Andrew Nucci	UCLA B	UCSD B	89	10
Asha Basu	McGill A	Ottawa	89	10
Brendan Bridle	Queen's	Western B	89	10
Rachel Fanous	Michigan B	CWRU B	89	10
Coby Tran	Chicago C	Northwestern C	89	10
Davis Johnson	Purdue B	Northwestern B	89	-5
Surya Dinesh	MIT	Dartmouth B	89	10
Foster Hughes	Minnesota A	Carleton College	89	-5
S. A. Shenoy	Georgia Tech D	WashU A	89	10
Chris Levesley	Warwick A	Bristol	89	10
Alan Li	Cornell C	Binghamton B	89	10
Snehan Saroch	Louisville A	Alabama B	90	10
Alec Riso	Cornell A	Cornell B	90	10
Nick Smemoe	North Carolina A	James Madison B	91	10
Arran Bligh	Oxford C	Imperial C	93	-5
Jacob Finley	Notre Dame A	Chicago E	96	10
Teigue Kelly	Penn State	Binghamton A	98	10
Nicholas Nguyen	Florida A	Florida C	100	10
Cade Reinberger	RIT	Rochester	100	10
Dustin Sanders	Chicago D	Illinois B	106	10
Matthew Forster	Dartmouth A	Brandeis B	106	10
Aisling Skeet	Durham	Southampton A	106	-5
Abby Smith	Berkeley C	Berkeley A	107	10
Amir Dolansky	Toronto E	Toronto G	107	-5
Jesse Mindel	NC State A	VCU	109	10
Andrew Vincent	Northwestern D	Indiana C	109	10
Imran Abdul Rahman	UCL	Imperial B	109	10
Paige Crawley	Oxford B	Cardiff	109	10
Danny Han	Stanford B	Berkeley D	111	10
Caleb Slusher	South Carolina A	NC State B	113	10
Samuel Li	William and Mary	North Carolina C	113	10
Sawyer Smith	Mississipi State	Vanderbilt B	113	10
Zachary Bornstein	Virginia Tech B	Liberty C	115	10
Camrun Scott	Murray State A	Texas B	115	10
Caleb West	Kentucky	Tennessee B	115	10
Florrie the Mononymous	Southampton A	Durham	115	10
Michał Gerasimiuk	Stanford A	Berkeley B	116	10
Jadon Pandian	UC Irvine	Arizona State	116	10
Ethan Ririe	UCSD C	UCSD A	116	10
Franklin Wu	Toronto C	Brock	116	0
Eva Mandelbaum	Guelph	Toronto F	116	10
Luke Sloan	McGill B	Western A	116	0
Victor Xu	Toronto G	Toronto E	116	10
AnnaMaria Donnelly	Central Florida B	Florida B	116	10
Travis Johnson	Pittsburgh	Ohio State A	116	10
Kabir Zaman	South Carolina B	Liberty B	116	10
Noah Fine	North Carolina B	Wake Forest	116	10
Alex Akridge	Indiana A	Chicago A	116	10
Azura Gollamudi	Northwestern B	Purdue B	116	10
Jeremy Ryu	Bowdoin B	Bowdoin A	116	10
Zoe Wang	Carleton College	Minnesota A	116	10
George Matsumura	Washington A	Washington B	116	10
Camden Walker	WashU B	Sewanee	116	10
Albert Nyang	LSE	Montpellier	116	10
Ollie Glin-Conway	Imperial C	Oxford C	116	10
Danny Fisher	Warwick B	Cambridge C	116	10

Summary

Tournament	Edition	Match	Heard	Conv. %	Neg %	Avg. Buzz
California (North)	Main Site	✓	3	100%	33%	111.33
California (South)	Main Site	✓	4	100%	50%	95.50
Canada	Main Site	✓	11	82%	9%	82.00
Florida	Main Site	✓	3	100%	0%	89.33
Great Lakes	Main Site	✓	5	100%	20%	86.60
Lower Mid-Atlantic	Main Site	✓	9	100%	0%	101.44
Midwest	Main Site	✓	8	100%	25%	88.63
Northeast	Main Site	✓	6	100%	0%	78.83
Overflow	Main Site	✓	4	100%	25%	91.75
South Central	Main Site	✓	2	100%	0%	86.50
Southeast	Main Site	✓	8	100%	0%	85.50
UK	Main Site	✓	12	100%	33%	84.92
Upstate NY	Main Site	✓	4	100%	0%	94.25