Packet D: Tossup 3

N-type inactivation of the slo1 (“slow-one”) type of these proteins can be described by the ball-and-chain model. (10[1]-5[1])One of these proteins uses the conserved (10[1])TVGYG (10[1])sequence as a “selectivity filter.” (10[2])The “long-lasting” type of (10[1])another class of these proteins is resistant to omega-conotoxins but not to dihydropyridines (“di-hydro-pyridines”). Metabotropic (10[1])glutamate receptors are contrasted (10[1])with these proteins that are alternatively activated by NMDA. (10[1]-5[2])Two-pore-domains (10[1])are found in the (-5[1])“leak” (10[2])type of these (-5[1])proteins, (10[2]-5[1])other types of which include (10[1])inward (10[1])and outward (10[1])rectifying (10[2])classes. Inhibitors of these proteins like tetrodotoxin (-5[2])are tested (10[3])using patch clamps. (10[3])Delayed voltage (-5[1])gating (10[1])of two different (10[1])types (10[1]-5[1])of these proteins (10[1])generates (10[1]-5[1])action potentials. (10[1]-5[2])For 10 points, name these membrane proteins (-5[1])that allow (10[1])charged (10[1])species to pass through. (10[2])■END■ (10[13]0[28])

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Summary