Round 10: Tossup 3
N-type inactivation of the slo1 (“slow-one”) type of these proteins can be described by the ball-and-chain model. One of these proteins uses the conserved TVGYG sequence as a “selectivity filter.” The “long-lasting” type of another class of these proteins is resistant to omega-conotoxins but not to dihydropyridines (“di-hydro-pyridines”). Metabotropic glutamate receptors are contrasted with these proteins that are alternatively activated by NMDA. Two-pore-domains are found in the “leak” type of these proteins, other types of which include inward and outward rectifying classes. Inhibitors of these proteins like tetrodotoxin are tested using patch clamps. Delayed voltage gating of two different types of these proteins generates action potentials. For 10 points, name these membrane proteins that allow charged species to pass through. ■END■
ANSWER: ion channels [accept calcium channels or Ca2+ channels or Ca channels; accept sodium channels or Na+ channels or Na channels; accept potassium channels or K+ channels or K channels; accept leak channels until read; accept voltage-gated channels until read; accept ligand-gated channels or lipid-gated channels; accept transmitter-activated channels; accept ionotropic receptors; prompt on channel proteins or transporter proteins by asking “for what molecules?”; prompt on integral membrane proteins or transmembrane proteins until read]
<CWRU A, Biology> | Packet D - UBC B, Oxford A, Waterloo B, CWRU A
= Average correct buzzpoint
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