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Packet D: Bonus 6

A 2015 study by Singh et al. found that HIV-1 prefers integration into genes where transcription and this other downstream process are both highly active. For 10 points each:
[10m] Name this process that involves the assembly of U1 to U6 snRNPs (“snurps”) into its namesake complex. HIV-1 hijacks host machinery to perform this process using four donor and seven acceptor sites.
ANSWER: RNA splicing [or word forms; accept alternative splicing; accept minor or major spliceosome assembly]
[10e] Early, unspliced HIV-1 transcripts are transported out of this organelle after Rev proteins bind exportin and Ran-GTP. Splicing factors are concentrated in Cajal bodies found in this organelle, which stores genomic DNA.
ANSWER: cellular nucleus [or cellular nuclei]
[10h] HIV-1 also evades this pathway by sequestering UPF1, a core component of its SURF complex. mRNA splicing errors are corrected by this pathway, which is triggered by the retention of exon-exon junction complexes.
ANSWER: nonsense-mediated decay [or NMD; prompt on mRNA decay; prompt on mRNA surveillance; reject “non-stop decay”]
<Oxford A, Biology> | Packet D - UBC B, Oxford A, Waterloo B, CWRU A

HeardPPBE %M %H %
6912.6196%26%4%

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Conversion

TeamOpponentPart 1Part 2Part 3TotalParts
Brandeis BBrandeis A010010E
BrownSouthern Connecticut State1010020ME
Harvard ABowdoin B1010020ME
Harvard BDartmouth A010010E
MITBowdoin A1010020ME
YaleDartmouth B1010020ME

Summary

TournamentEditionMatchHeardPPBE %M %H %
California (North)Main Site✓310.00100%0%0%
California (South)Main Site✓415.00100%50%0%
FloridaMain Site✓310.00100%0%0%
Great LakesMain Site✓410.0075%25%0%
Lower Mid-AtlanticMain Site✓912.2289%33%0%
MidwestMain Site✓912.22100%11%11%
NortheastMain Site✓616.67100%67%0%
OverflowMain Site✓410.00100%0%0%
South CentralMain Site✓210.0050%50%0%
SoutheastMain Site✓711.43100%14%0%
UKMain Site✓615.00100%33%17%
Upper Mid-AtlanticMain Site✓815.00100%38%13%
Upstate NYMain Site✓410.00100%0%0%