Round 8: Tossup 10
Electroformation is used to generate the “giant unilamellar” type of these structures. These structures can be assembled using a protein that has “helix-break-helix” motifs and is called caveolin-1. A protein involved in assembling another type of these structures contains PIP2 (“pip-two”)-binding ANTH domains and links AP2 adaptor complexes with a triskelion-shaped protein that coats these structures. Rab GTPases (“G-T-P-aces”) help tether these structures prior to SNARE (“snair”)-mediated fusion. Sec13/31 (“seck-13-31”) is recruited to assemble COPII (“cop-two”) complexes around these structures, which are analogous to their clathrin-coated types. Receptor-mediated endocytosis forms these structures, which also compartmentalize cargo by the trans-Golgi network. For 10 points, name these membrane-bound structures used for trafficking. ■END■
ANSWER: vesicles [accept transport or secretory or intracellular vesicles; accept extracellular vesicles or EVs or exosomes; accept giant unilamellar vesicles or GUVs until read; accept COPI-, COPII-, or clathrin-coated vesicles; accept multivesicular bodies or MBVs; accept late or early endosomes; accept liposomes; prompt on lipid membranes (until read) or lipid bilayers or phospholipids or lipids; reject “micelles”; reject “organelles” or “lysosomes” or “peroxisomes”] (The third sentence refers to AP180 or CALM or clathrin-assembly lymphoid myeloid leukemia protein.)
<Ohio State C, Biology> | Packet H - Yale A, Ohio State C, Illinois C, Virginia Tech B, MIT A
= Average correct buzzpoint
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